A Bone marrow transplant, also known as a stem cell transplant, is a complex medical procedure that replaces damaged or diseased bone marrow with healthy bone marrow cells. Bone marrow is the spongy tissue found inside bones, responsible for producing blood cells.

These are used to treat various conditions that affect the blood and immune system, including Leukemia, lymphoma, multiple myeloma, sickle cell anemia, thalassemia, aplastic anemia, and Immune deficiency disorders. 

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Extensive testing identifies a suitable HLA-matched donor. Donor stem cells are collected via bone marrow aspiration, stimulated by medications, and infused into the patient’s bloodstream to engraft in the bone marrow. Chemotherapy/radiation destroys diseased marrow, allowing healthy cells to grow. The process weakens the immune system, requiring close monitoring. 

Donor immune cells may attack recipient tissues, increasing infection risk and organ damage. Success rates vary based on leukemia type, patient health, and donor availability. Transplants can enhance survival and reduce relapse risk. It’s crucial to discuss the benefits and risks with your doctor before undergoing this complex procedure.

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