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 Tramadol is a synthetic opioid analgesic that operates primarily within the central nervous system. Its effectiveness stems from multiple mechanisms: First, it weakly activates mu-opioid receptors, which helps to alter the perception and transmission of pain. Second, it inhibits the reuptake of serotonin and norepinephrine, two key neurotransmitters that play a crucial role in pain regulation. By increasing their levels in the synapses, tramadol effectively reduces the intensity of pain signals.

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– Cancer Pain: In patients with cancer, tramadol is utilized as part of a holistic pain management strategy, addressing both acute and chronic pain scenarios.

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